Mike Greenberg
В роли: Self - Co-Host

Mike Golic
В роли: Self - Co-Host

Kristen Balboni
В роли: Self - Researcher, Mike & Mike

Ryan Braun
В роли: Self - Milwaukee Brewers Left Fielder (хроника)

Jim Calhoun
В роли: Self - Former University of Connecticut Men's Basketball Coach (голос)

Liam Chapman
В роли: Self - Producer, Mike & Mike

Tom Izzo
В роли: Self - Michigan State University Men's Basketball Coach (голос)

Дерек Джетер
В роли: Self - New York Yankees Shortstop (хроника)

Johnny Manziel
В роли: Self - Former Texas A&M University Quarterback (хроника)

Rick Pitino
В роли: Self - University of Louisville Men's Basketball Coach (голос)

Cal Ripken
В роли: Self - Baseball Hall of Famer (голос) (как Cal Ripken Jr.)

Bob Uecker
В роли: Self - Milwaukee Brewers Broadcaster (archive sound)

Mike Urrunaga
В роли: Self - Social Media Producer, Mike & Mike

Mike Zimmer
В роли: Self - Minnesota Vikings Head Coach (archive sound)